+7000 Free games online for cooking food, serve meals and drinks dress up, fashion and makeover Celebrities Caring ability, use your mental and physical skills action, shooting and fighting adventure, arcade and classic puzzles and sudokus car racing and driving motorcycles, motobikes and quads sports and competition Halloween, Easter, Christmas and holidays Mathematics Music Typing games to learn to type fast. Puzzle Madness - Spongebob with Squarepantsįree fun games for boys girls kids teens child children teenagers interDidactica Spongebob Squarepants - spot the difference The program's installer file is generally known as SpongeBob Squarepants Deep.exe. SpongeBob Squarepants Deep Sea lies within Games, more precisely Arcade. The following version: 2.0 was the most frequently downloaded one by the program users. Deep Sea Smashout Delivery Dilemma Demolition Sponge Dirty Bubble Busters Dunces and Dragons Dutchmans Dash Flip or Flop Frosty Fling Fang In There. Spongebob Squarepants fall fall fall away Spongebob deep sea smashout Views 4 Saved 3 Size 1.57 M Extension. SpongeBob Squarepants Deep Sea 2.0 was free to download from our software library. SpongeBob SquarePants jellyfish shuffleboard Help Spongeboband Gary SMASH their way off the sea floor in the SpongebobDeep Sea Smashout game Help Spongeboband Gary break through the coral reef. Sponge Bob Square Pants Bikini Bottom Bust Up Sponge Bob flying with jellyfish jigsaw puzzle SpongeBob the greatest fighter jigsaw puzzle Sponge Bob 10th Anniversary jigsaw puzzle SpongeBob oldest living bubble jigsaw puzzle Sponge Bob Squarepants: Deep sea smashout Februspongebob 2 player games, spongebob 2 player games free games, spongebob 2 player games flash games, free flash games, spongebob 2 player games online games, play spongebob 2 player games game. Have fun at the sea bottom at Pineapple Home, in the Krusty Krab and Bikini Bottom. Instructions: Right / Left Arrows - Move Right / Left. Games of various kinds, adventure, puzzles, clothing, costumes, skill, sports, coloring and more. Spongebob / Kids / Break SpongeBob: Deep Sea Smashout Info Description: A game of Breakout with Spongebob's head as the paddle. 148 SpongeBob SquarePants games with his friends Gary, Patrick, Sandy, Squidward and all the characters in the series and movies.
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Phillips and UNSW Medicine collaborator Professor David Goldstein, which was funded by a recently awarded Cancer Institute NSW Translational Program Grant. The team's findings have formed the foundation for a clinical trial led by A/Prof. This therapy is advantageous because our nano-drug is tiny and able to penetrate the scar tissue in pancreatic cancer," co-first author Associate Professor Joshua McCarroll from the Children's Cancer Institute says. "We also used our cutting-edge nanomedicine we developed in a multi-disciplinary collaboration with engineers - UNSW Professor Cyrille Boyer and University of Queensland Professor Thomas Davis - to deliver a gene therapy to inhibit SLC7A11. "In other words, we have identified a novel 'dual cell' therapeutic target - tackling both the tumour cells and their helpers - which overcomes the current limitations of standard chemotherapy." The team used several complementary models to improve the clinical translatability of their findings, including patient-derived pancreatic cancer cell lines and helper cells, 3D at-the-bench models including an explant model that maintains pieces of human pancreatic tumour tissue, and multiple mouse models of pancreatic cancer. SLC7A11 has been studied in pancreatic cancer cells before, but this is the first piece of research to show that it plays a critical role in non-tumour helper cells, too. Phillips' lab who led the experimental work. "We found that switching off SLC7A11 in mice with pancreatic tumours directly killed pancreatic cancer cells, reduced the spread of tumour cells throughout their body and decreased the scar tissue fortress," says Dr George Sharbeen, a postdoc researcher in A/Prof. In today's paper, the team demonstrates their novel way to metabolically rewire helper cells by targeting one particular protein called SLC7A11, which in turn shuts off the cells' tumour-promoting activity and reduces the scar tissue they produce. "Our approach hits both the tumour cells and the helper cells, so it's ideal for overcoming the aggressiveness and drug resistance of the disease." Yet, these helper cells have been ignored in current treatment strategies," A/Prof. "This scar tissue is produced by critical 'helper cells' - also called cancer-associated fibroblasts - which cancer cells recruit to support their growth and spread. Pancreatic cancer is notoriously difficult to treat because of the dense scar tissue surrounding tumours - the tissue acts like a fortress that blocks chemotherapy delivery. "But our latest advance means today I am the most optimistic and hopeful I have been in my career." "Pancreatic cancer has seen minimal improvement in survival for the last four decades - and without immediate action, it is predicted to be the world's second biggest cancer killer by 2025," says senior author Associate Professor Phoebe Phillips from UNSW Medicine & Health. You can even perform basic editing operations like cut, copy, paste, and delete. The math and science software lets you embed text messages which can be customized in the form of size, font, and color. Download The Geometer's Sketchpad to improve your knowledge concerning mathematical concepts. You are also able to change their attributes in terms of opacity, label, plot, function, together with transformation functions such as animation and rotation. Along with this, the geometry software enables you to measure angles and midpoints of shapes to create and solve equations. You can draw geometrical shapes to visualize your math problems. On the other hand, middle school students can build their readiness for algebra by exploring the rate of change, ratio and proportion, and functional relationships through tabular, numeric and graphical representations. Using The Geometer's Sketchpad for Windows, elementary students can manipulate their dynamic models of number lines, fractions, and geometric patterns. The educational software is targeted towards students from third grade to college and provides a tangible way to learn mathematics in a more engaging manner. The teaching tool’s main purpose is to support the study of mathematical theory with the aid of visual elements. Separate installation codes for school boards, teachers/students.The Geometer's Sketchpad is a comprehensive application to learn geometry as well as elementary and middle school algebra. Sketchpad 5 is a downloadable application that can be installed over a network.New JavaSketchpad applets can incorporate algebraic functionality and action buttons.The new Information tool gives quick access to definitions and properties of objects.Sketchpad Version 5 supports Unicode and video game-quality graphics through a tenfold increase in data compression, high-performance graphics acceleration, and advanced data handling.All your Version 4 sketches and activities will still work - they’ll just work faster.The layout of mathematical expressions is improved - you can use Greek symbols, multiple or nested subscripts in labels, and other mathematical notation.Mathematical italicization is used in labels, measurements, calculations, and equations.Text style and size on axis tick marks are adjustable.Expanded line weights, line strokes, and point sizes allow for age-appropriate sizing of objects.New nonlinear transformations can be defined and added to the Transform menu.Multiple transformations can be combined into a single custom transformation.Angles can be defined by two intersecting rays or segments, and can also be defined to be reflex angles greater than 180° or trigonometric angles (between –2π and 2π radians).Easily construct polygons and their interiors with the new Polygon tool.Choose a grid with trigonometric labels, create and listen to dynamic audible functions, and graph parametric functions.Construct entire families of functions and families of curves, parameterized either geometrically or numerically.
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Slender: The Arrival is also planned for console release in Q1 2014. Slender: The Arrival is rated T and will release on Steam for PC via digital download on Octofor $9.99. Follow the clues and unravel the mystery, that is, if you can survive. Armed with a camcorder, flashlight and your wits – players are enveloped in a world of sensory deprivation and audio cues that create an ominous backdrop perfect for fostering a healthy dose of tension and paranoia. The road is long and full of peril – implied, imagined and, of course – real.īuilding on the successful independent PC release earlier this year, the Steam iteration of Slender: The Arrival delves deeper into the story established in Slender: The Eight Pages and features extended levels and a new character to contend with. About Press Copyright Contact us Creators Advertise Developers Terms Privacy Policy & Safety How YouTube works Test new features Press Copyright Contact us Creators. Follow the clues and document your experience via camcorder as you unravel the mystery while evading the ominous forces that shadow your every move. Players take on the role of Laura, an unsuspecting realtor helping her friend Kate sell her scenic property, but things quickly take a turn for the worse when Laura arrives to find Kate missing. Written by the creative team behind Marble Hornets, this latest iteration in the Slender Man universe builds on the canon established by the original web-series, with some new twists and extended content. four out of fifty - eight pages in which trituration in a mortar produces. Not for the weak of heart, Slender: The Arrival is also compatible with Oculus Rift, offering a truly heart-pounding and immersive experience. Hack's New and telligence, but most likely to mislead, when it spond to the. Slender: The Arrival wraps players in a dark, foreboding atmosphere and a story fraught with terror, paranoia and other-worldly forces. 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It must be in usable condition regardless of whether the Product Owner decides to actually release it.īurndown charts are graphs that give an overview of progress over time while completing a project.It must meet the Scrum Team’s Definition of “Done.”.The Increment is the sum of all the Product Backlog items completed during a Sprint and all previous Sprints.Īt the end of a Sprint, the new Increment must be “Done,” which means: Here is some examples: Definition of Done (DOD) Increment It typically contains quality criteria, constraints and overall non-functional requirements. Thus, the Definition of Done is a shared understanding of the Scrum Team on the meaning of work to be complete. Instead of repeatedly defining these criteria with each item, it has proven to be useful to collect these criteria in one place: the Definition of Done. Many criteria apply to all or many Product Backlog items. Sprint backlog Definition of DoneĮvery Product Backlog item has acceptance criteria that define measurably what must be met when the item is declared to be done. The Sprint Backlog makes visible all of the work that the Development Team identifies as necessary to meet the Sprint Goal. The Sprint Backlog defines the work the Development Team will perform to turn Product Backlog items into a “Done” Increment. The Sprint Backlog is a forecast by the Development Team about what functionality will be in the next Increment and the work needed to deliver that functionality. The Sprint Backlog is the set of Product Backlog items selected for the Sprint plus a plan for delivering the product Increment and realizing the Sprint Goal. Thus, product backlog is consistently updated to reflect what the product needs to be most useful to the target users. change in business requirements, market conditions, or technology. Typically, the requirements of a product keep changing, i.e. Product backlog owned by the Product Owner (PO) which consists of a lists all features, functions, requirements, enhancements, and fixes that constitute the changes to be made to the product in the future releases. Product BacklogĪ product backlog is a list of all the things that are required in the product and it is a dynamic and best understood requirements for any changes to be made to the product. It is however in large part of interest to the Product Owner to support this process by having clear business goals for the coming Sprint, which can also make ordering the Product Backlog a lot easier by providing Focus. It is achieved during the Sprint by implementing forecasted product backlog items, and it provides guidance to the development team as to why product increments should be built.Īs per the Scrum Guide, the responsibility for crafting a Sprint Goal is for the Scrum Team. Sprint Goalġ4 PM Sprint goals help focus the sprint. Everyone should be able to memorize the Product Vision therefore it must be short and precise. It sets the overall direction and guides the Scrum Team. The Product Vision is an artifact to define the long-term goal of the project/product. It features scrum tools like user story map, product backlog management, sprint backlog management, task management, daily scrum meeting, sprint planning tool, sprint review tool, sprint retrospective tool, burndown, impediment, stakeholder and team management. Our readers have come to expect excellence from our products, and they can count on us to maintain a commitment to producing rigorous and innovative information products in whatever forms the future of publishing may bring.A powerful scrum software that supports scrum project management. Through our commitment to new products-whether digital journals or entirely new forms of communication-we have continued to look for the most efficient and effective means to serve our readership. Since the late 1960s, we have experimented with generation after generation of electronic publishing tools. The Press's enthusiasm for innovation is reflected in our continuing exploration of this frontier. We were among the first university presses to offer titles electronically and we continue to adopt technologies that allow us to better support the scholarly mission and disseminate our content widely. Among the largest university presses in the world, The MIT Press publishes over 200 new books each year along with 30 journals in the arts and humanities, economics, international affairs, history, political science, science and technology along with other disciplines. If you and your recipient have PGP key sets and you send a message from your Mac or PC with PGP email encryption active, forget about you or your recipient reading that message on any smart phone, any web mail or a system that has not had PGP installed. PGP Mail integration suffers from assumption problems with the automatic encryption of messages based upon the availability of your recipient's (and your) PGP keys on the PGP server in the sky. Good on stability but unfortunately one of the main features, the buttons in Apple Mail & Entourage, is missing. Rebuild the directory of the PGP Disk Image files." Sorry I don't have a workaround for you to Nothing do be done to get past whateverĬhanges they are making. Operating system in case the user wants to utilize the Whole DiskĮncryption feature. My guess is that they are modifying something in the low-level of the Uninstall PGP - and everything is normal. Impossible! This indicates that the partition map was being obscuredįrom our view. On the computer, had no partition map! This, of course, would be Main hard drive, that was currently running the active operating system Of the computer, not just PGP-modified disks.įor example, with PGP installed, DiskWarrior showed that my computer's IORegistry (which is what keeps track of all hardware and mountedĭevices on the computer) and has an effect on the entire functionality When the new PGP is installed, it does something to modify the "Ok, I've installed PGP onto my computer and I see the basic problem. I wrote to Alsoft to ask if they knew anything. I was already pissed off with PGP because somehow I found myself no longer able to run DiskWarrior on PGP Disks. So in cases where I would create a PGP Disk and burn it to DVD, it would appear I am out of luck, (Unless I can find a way to keep using 10.1.1.10 in Lion.) I now send documents by encrypted PDF in Preview but that still doesn't cover all of the uses I would put PGP to.įor example, Lion Whole Disk Encryption will only work when there is a system installed. I have paid version 10.1.1.10 but can I find the upgrade button to 10.1.2? Hell no!įor most needs, Lion's new Whole Disk Encryption will do fine but no more sending PGP disk attachments, it looks like. Now, Norton has nailed the coffin shut by thumbing their noses at Mac users. Those bastards at PGP were already the gold standard for making it impossible to reach them. This release supports installation of Symantec Desktop Encryption, formerly known as PGP Desktop, on systems running Mac OS X 10.8 (Mountain Lion).įor a list of issues that have been resolved in this release, please go to the Symantec Knowledgebase and search for TECH166098, "Symantec Encryption Desktop Resolved Issues." For a detailed map of old product names to new ones, refer to the Symantec Knowledgebase article TECH197084. What's New in Symantec Encryption Desktop 10.3 What's New in Symantec Encryption Desktop Version 10.3 for Mac OS Xīuilding on Symantec Corporation’s proven technology, Symantec Encryption Desktop 10.3 for Mac OS X includes numerous improvements and the following new features. 10.3 is out but it's newly RENAMED as Symantec Encryption Desktop!: Oetker Baking Powder (10-pack) 531 Amazon's Choice in Baking Powder 13 offers from 6.51 Product details Is Discontinued By Manufacturer : No Product Dimensions : 5.31 x 3.74 x 1.57 inches 8. Lake Natron Photographs Fine Art America. As isolated as the lake is (it wasn't even discovered by Europeans until 1954), there are no protections in place for the lake or its threatened flamingo population.įollow Marc Lallanilla on Twitter and Google+. German Dr.Oetker NATRON- 5 sachets-25 g-IMPORTED-SHIPPING from USA 21 4 offers from 6.97 Dr. The serenity of Lake Natron - and its flamingo population - are threatened by a proposed hydroelectric power plant on the Ewaso Ngiro River, the main river feeding the lake. Made from commodity materials including aluminum, iron, manganese, and sodium-ions (68 of the earths surface is covered with salt water) Natrons cells. As shallow lakes in a hot climate, their water temperatures can reach as high as 106 degrees Fahrenheit (41 degrees Celsius). Both are terminal lakes that do not drain out to any river or sea they are fed by hot springs and small rivers. Natron is a natural deposit that forms in salt. Lake Natron is one of two alkaline lakes in that area of East Africa the other is Lake Bahi. Sodium bicarbonate (NaHCO3) is an alkaline chemical compound that occurs naturally in a substance called natron. The flamingos' nests are built on small islands that form in the lake during the dry season. During breeding season, more than 2 million lesser flamingos ( Phoenicopterus minor) use the shallow lake as their primary breeding ground in Africa. |
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